Product & ReviewsAntibodies

Anti-Mouse CD8a (Clone 53-6.7) - DyLight® 594

Product Details

Cat. No.
C1740- 50 µg
Clonality
Monoclonal
Host
Rat
Leinco Technologies

The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our  Antibody Directory.

Description

CD8 is made up of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8 is part of the Ig superfamily that expresses primarily as CD8a homodimers. CD8a is a 32-34 kD type I glycoprotein that can also form heterodimers with CD8b. CD8 is an antigen co-receptor on T cells that mediates efficient cell to cell interactions within the immune system. CD8 coupled with the T cell receptor on the T lymphocyte recognizes an antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The CD8 co-receptor also plays a role in T cell signaling by interacting with Lck (lymphocyte-specific protein tyrosine kinase) which leads to the activation of transcription factors that affect the expression of certain genes.

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Antigen: Lyt 2 is present on the surface of most thymocytes and a subpopulation of mature T-lymphocytes which include most T suppressor/cytotoxic cells.
  • Clone: 53-6.7
  • Conjugate: DyLight® 594
  • Isotype: IgG2a
  • Gene: 12525

Handling

  • Quantity: 50 µg
  • Storage: This DyLight® 594 conjugate is stable when stored at 2-8°C. Do not freeze.

Applications

  • In Situ Hybridization (ISH)
Specificity rating
Sensitivity rating
Quality rating
Write your own review

Product Overview

Links