Product & ReviewsAntibodies
Anti-Mouse CTLA-4 (CD152) - Biotin
Product Details
- Cat. No.
- C400-50 µg
- Clonality
- Polyclonal
- Host
- Goat
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Description
CTLA-4 is a 33 kD member of the Ig superfamily similar to CD28 in amino acid sequence, structure, and genomic organization. CTLA-4 is a protein receptor that functions as an immune checkpoint and downregulates immune responses. It is involved in the development of protective immunity and thymocyte regulation, in addition to the induction and maintenance of immunological tolerance. CTLA-4 has therapeutic potential both as an agonist to reduce immune activity, and an antagonist to increase immune activity.
Biological Information
- Clonality: Polyclonal
- Host: Goat
- Reactivity: Mouse
- Antigen: CTLA-4 is expressed on activated T and B lymphocytes.
- Conjugate: Biotin
- Gene: 12477
Handling
- Quantity: 50 µg
- Storage: The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Applications
- Immunohistochemistry (IHC)
- Neutralization (Neut)
- Western Blotting (WB)