Product & ReviewsAntibodies
Anti-Mouse CTLA-4 - PE
Product Details
- Cat. No.
- C2445- 50 µg
- Clonality
- Monoclonal
The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our Antibody Directory.
Description
CTLA-4 is a 33 kD member of the Ig superfamily similar to CD28 in amino acid sequence, structure, and genomic organization. CTLA-4 is a protein receptor that functions as an immune checkpoint and downregulates immune responses. It is involved in the development of protective immunity and thymocyte regulation, in addition to the induction and maintenance of immunological tolerance. CTLA-4 has therapeutic potential both as an agonist to reduce immune activity, and an antagonist to increase immune activity.
Biological Information
- Clonality: Monoclonal
- Reactivity: Mouse
- Antigen: CTLA-4 is expressed on activated T and B lymphocytes.
- Clone: UC10-4F10-11
- Conjugate: R-phycoerythrin (PE)
- Isotype: IgG1
- Gene: 12477
Handling
- Quantity: 50 µg
- Storage: This R-phycoerythrin (R-PE) conjugate is stable when stored at 2-8°C. Do not freeze.
Applications
- In Situ Hybridization (ISH)