Product & ReviewsAntibodies

Anti-Mouse CXCL10 - Biotin

Product Details

Cat. No.
I-276
Clonality
Polyclonal
Host
Goat
Leinco Technologies

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Description

Chemokine (C-X-C motif) ligand 10 (CXCL10) or IP-10 is a small cytokine belonging to the CXC chemokine family. CXCL10 is secreted by several cell types in response to IFN-γ. These cell types include monocytes, endothelial cells and fibroblasts.1 CXCL10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis.2,3 CXCL10 plays a role in the regulation of tubular cell proliferation following renal ischemia-reperfusion injury.4

Biological Information

  • Clonality: Polyclonal
  • Host: Goat
  • Reactivity: Mouse
  • Conjugate: Biotin
  • Gene: 15945

Handling

  • Quantity: 50 µg
  • Storage: The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.

Applications

  • Immunohistochemistry (IHC)
  • Neutralization (Neut)
  • Western Blotting (WB)
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