Product & ReviewsAntibodies

Anti-Mouse Ephrin-B1 - Biotin

Product Details

Cat. No.
E286
Clonality
Polyclonal
Host
Goat
Leinco Technologies

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Description

Ephrin-B1 (EFNB1) is a glycoprotein that is expressed on neuroepithelial cells1 and post-synaptically on dendritic spines in the cortex, supporting a role in synaptic plasticity in this region.2 Ephrin-B1 is also highly expressed on developing peripheral nerve fibers including auditory and vestibular (statoacoustic) and dorsal root ganglion nerve fibers and provides guidance signals to these cells.3 Ephrin-B1 participates in cell-cell repulsive and attractive signaling together with its Eph receptor.4 Tyrosine phosphorylation of ephrin-B1 promotes invasion of cancer cells in vivo and is a potential therapeutic target in some types of gastrointestinal cancers.5

Biological Information

  • Clonality: Polyclonal
  • Host: Goat
  • Reactivity: Mouse
  • Conjugate: Biotin
  • Gene: 13641

Handling

  • Quantity: 50 µg
  • Storage: The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.

Applications

  • ELISA (ELISA)
  • Western Blotting (WB)
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