Product & ReviewsAntibodies
Anti-Mouse γ/δ (TCR) - DyLight<sup>®</sup> 488
Product Details
- Cat. No.
- T599
- Clonality
- Monoclonal
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Description
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
Biological Information
- Clonality: Monoclonal
- Reactivity: Mouse
- Antigen: γδ TCR expression is observed on a subset of cells in the thymus, intestinal epithelium, skin, liver, peripheral lymphoid tissues, and peritoneum. The γδ TCR is involved in the antigen recognition of some bacterial or tumor-associated antigens presented by MHC class I.
- Clone: UC7-13D5
- Conjugate: DyLight® 488
- Isotype: IgG
Handling
- Quantity: 100 µg, 200 µg, 50 µg
- Storage: This DyLight® 488 conjugate is stable when stored at 2-8°C. Do not freeze.
Applications
- In Situ Hybridization (ISH)