Anti-Mouse γ/δ (TCR) - Purified <i>In vivo </i>GOLD™ Functional Grade

The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.

• Clonality: Monoclonal
• Reactivity: Mouse
• Antigen: γδ TCR expression is observed on a subset of cells in the thymus, intestinal epithelium, skin, liver, peripheral lymphoid tissues, and peritoneum. The γδ TCR is involved in the antigen recognition of some bacterial or tumor-associated antigens presented by MHC class I.
• Clone: UC7-13D5
• Conjugate: GOLD, Low Endotoxin Functional Formulation
• Isotype: IgG

• Quantity: 1.0 mg, 100 mg, 25 mg, 5.0 mg, 50 mg
• Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

• Blocking (BA)
• Western Blotting (WB)