Product & ReviewsAntibodies
Anti-Mouse γ/δ (TCR) - Purified <i>In vivo </i>GOLD™ Functional Grade
Product Details
- Cat. No.
- T352- 50 mg
- Clonality
- Monoclonal
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Description
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
Biological Information
- Clonality: Monoclonal
- Reactivity: Mouse
- Antigen: γδ TCR expression is observed on a subset of cells in the thymus, intestinal epithelium, skin, liver, peripheral lymphoid tissues, and peritoneum. The γδ TCR is involved in the antigen recognition of some bacterial or tumor-associated antigens presented by MHC class I.
- Clone: UC7-13D5
- Conjugate: GOLD, Low Endotoxin Functional Formulation
- Isotype: IgG
Handling
- Quantity: 50 mg
- Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Applications
- Immunohistochemistry (IHC)
- In Situ Hybridization (ISH)
- Mass Cytometry (CyTOF)
- Western Blotting (WB)