Product & ReviewsAntibodies

Anti-Mouse γ/δ (TCR) - Purified <i>In vivo </i>GOLD™ Functional Grade

Product Details

Cat. No.
T352- 50 mg
Clonality
Monoclonal
Leinco Technologies

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Description

The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.

Biological Information

  • Clonality: Monoclonal
  • Reactivity: Mouse
  • Antigen: γδ TCR expression is observed on a subset of cells in the thymus, intestinal epithelium, skin, liver, peripheral lymphoid tissues, and peritoneum. The γδ TCR is involved in the antigen recognition of some bacterial or tumor-associated antigens presented by MHC class I.
  • Clone: UC7-13D5
  • Conjugate: GOLD, Low Endotoxin Functional Formulation
  • Isotype: IgG

Handling

  • Quantity: 50 mg
  • Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Applications

  • Immunohistochemistry (IHC)
  • In Situ Hybridization (ISH)
  • Mass Cytometry (CyTOF)
  • Western Blotting (WB)
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