Product & ReviewsAntibodies

Anti-Mouse gp130 - Biotin

Product Details

Cat. No.
G690-50 µg
Clonality
Polyclonal
Host
Goat
Leinco Technologies

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Description

Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta or CD130) is a transmembrane protein which is the founding member of the class of tall cytokine receptors. It forms one subunit of type I cytokine receptors within the IL-6 receptor family. It is often referred to as the common gp130 subunit, and is important for signal transduction following cytokine engagement.1 Gp130 signals are mediated by tyrosine kinases of the JAK family and by their binding partners, transcription factors of the STAT family.2 Gp130 signaling is very important for osteoblast function and calcium homeostasis.3

Biological Information

  • Clonality: Polyclonal
  • Host: Goat
  • Reactivity: Mouse
  • Conjugate: Biotin
  • Gene: 16195

Handling

  • Quantity: 50 µg
  • Storage: The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.

Applications

  • ELISA (ELISA)
  • Western Blotting (WB)
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