Product & ReviewsAntibodies

Anti-Mouse ICAM-1 (CD54) (Clone BE29G1) - Purified <i>In vivo </i>GOLD™ Functional Grade

Product Details

Cat. No.
C391- 100 mg
Clonality
Monoclonal
Host
Rat
Leinco Technologies

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Description

Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein1 and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines.2 ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.3

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Antigen: The CD54 antigen is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes. It has been demonstrated that ICAM-1 enhances T-cell activation.
  • Clone: BE29G1
  • Conjugate: GOLD, Low Endotoxin Functional Formulation
  • Isotype: IgG2a
  • Gene: 15894

Handling

  • Quantity: 100 mg
  • Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Applications

  • In Situ Hybridization (ISH)
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