Product & ReviewsAntibodies
Anti-Mouse ICAM-1 (CD54) (Clone BE29G1) - Purified <i>In vivo </i>GOLD™ Functional Grade
Product Details
- Cat. No.
- C391- 50 mg
- Clonality
- Monoclonal
- Host
- Rat
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Description
Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein1 and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines.2 ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.3
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Mouse
- Antigen: The CD54 antigen is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes. It has been demonstrated that ICAM-1 enhances T-cell activation.
- Clone: BE29G1
- Conjugate: GOLD, Low Endotoxin Functional Formulation
- Isotype: IgG2a
- Gene: 15894
Handling
- Quantity: 50 mg
- Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Applications
- Depletion (Dep)
- Immunohistochemistry (IHC)
- In Situ Hybridization (ISH)
- Western Blotting (WB)