Product & ReviewsAntibodies
Anti-Mouse IFNAR-1 - PE
Product Details
- Cat. No.
- I-1033- 25 µg
- Clonality
- Monoclonal
- Host
- Mouse
The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our Antibody Directory.
Description
IFNAR1 is a type I membrane protein, that in conjunction with IFNAR2, makes up the heterodimeric receptor that binds all type I IFNs, which includes IFN α and β. Binding and activation of the receptor stimulates Janus protein kinases, which leads to the phosphorylation of several other proteins, namely STAT1 and STAT2. IFNAR1 has also been shown to interact with PRMT1 and Tyrosine kinase 2. Type I IFNs are a family of cytokines that have been shown to promote anti-viral, anti-microbial, anti-tumor and autoimmune responses In vivo.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Mouse
- Antigen: IFNAR1 and IFNAR2 are coexpressed on nearly all cells.
- Clone: MAR1-5A3
- Conjugate: R-phycoerythrin (PE)
- Isotype: IgG1
- Gene: 159759
Handling
- Quantity: 25 µg
- Storage: This R-phycoerythrin (R-PE) conjugate is stable when stored at 2-8°C. Do not freeze.
Applications
- In Situ Hybridization (ISH)