Anti-Mouse IL-1α - Purified <i>In vivo </i>GOLD™ Functional Grade
Product Details
- Cat. No.
- I-428- 5.0 mg
- Clonality
- Monoclonal
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Description
Mouse IL-1alpha is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine.
Biological Information
- Clonality: Monoclonal
- Reactivity: Mouse
- Clone: ALF-161
- Conjugate: GOLD, Low Endotoxin Functional Formulation
- Isotype: IgG1
- Gene: 16175/a>
Handling
- Quantity: 5.0 mg
- Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Applications
- Fluorescent Assay (FA)
- In Situ Hybridization (ISH)