Product & ReviewsAntibodies
Anti-Mouse IL-1β-Purified
Product Details
- Cat. No.
- I-436- 500 µg
- Clonality
- Monoclonal
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Description
Interleukin 1 beta (IL1 beta) is a proinflammatory cytokine belonging to IL1 family that is synthesized as a precursor. The IL1 beta precursor form is not biologically active. It is expressed mainly by stimulated macrophages and monocytes.1,2 IL1 beta is known to be a mediator in inflammatory response and to be involved in a variety of cellular activities, proliferation, differentiation and apoptosis. It has been recently found that IL1 beta is a major cause of severe inflammation in the mouse model of Crohns disease which makes IL1 beta an important target for this disease.3
Biological Information
- Clonality: Monoclonal
- Reactivity: Mouse
- Clone: B122
- Conjugate: Purified
- Isotype: IgG
Handling
- Quantity: 500 µg
- Storage: This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Applications
- ELISA (ELISA)
- In Situ Hybridization (ISH)