Product & ReviewsAntibodies

Anti-Mouse IL-4 (Clone BVD6-24G2) - Biotin

Product Details

Cat. No.
I-1109- 500 µg
Clonality
Monoclonal
Host
Rat
Leinco Technologies

The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our  Antibody Directory.

Description

IL-4 is a 15-19 kD pleiotropic immune cytokine secreted by activated TH2 cells. It has many biological roles, including the regulation in humoral and adaptive immunity, the inhibition of bone resorption, the stimulation of activated B-cell and T-cell proliferation, and initiation of allergic responses. Moreover, IL-4 induces a positive feedback loop by stimulating differentiation of naive helper T cells, or Th0 cells, to Th2 cells which in turn secrete more IL-4. Increased IL-4 production and overproduction of IL-4R are found in many cancers. IL-4 has a significant effect on tumor progression by increasing apoptosis resistance via tumor growth enhancement. IL-4 may also play a part in the immune dysregulation that occurs in most HIV-1 infected patients.

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Clone: BVD6-24G2
  • Conjugate: Biotin
  • Isotype: IgG1
  • Gene: 16189

Handling

  • Quantity: 500 µg
  • Storage: This Biotin conjugate is stable when stored at 2-8°C. Do not freeze.

Applications

  • Blocking (BA)
  • Immunoprecipitation (IP)
  • In Situ Hybridization (ISH)
  • Mass Cytometry (CyTOF)
Specificity rating
Sensitivity rating
Quality rating
Write your own review

Product Overview

Links