Product & ReviewsAntibodies
Anti-Mouse MAdCAM-1 - DyLight® 488
Product Details
- Cat. No.
- M1406-100 µg
- Clonality
- Monoclonal
- Host
- Rat
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Description
Mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) is a multifunctional type l transmembrane adhesion molecule that is expressed selectively at venular sites of lymphocyte extravasation into mucosal lymphoid tissues and lamina propria, where it directs local lymphocyte trafficking.1 MAdCAM-1 is involved in the normal recirculation of lymphocytes between the blood and the gastrointestinal tract.2 MAdCAM-1 may be a relevant tissue-specific therapeutic target for the modulation of inflammatory bowel disease activity.3
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Mouse
- Clone: MECA-367
- Conjugate: DyLight® 488
- Isotype: IgG2a
- Gene: 17123
Handling
- Quantity: 100 µg
- Storage: This DyLight® 488 conjugate is stable when stored at 2-8°C. Do not freeze.
Applications
- In Situ Hybridization (ISH)