Product & ReviewsAntibodies

Anti-Mouse TCR β chain - DyLight® 550

Product Details

Cat. No.
T669- 50 µg
Clonality
Monoclonal
Leinco Technologies

The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our  Antibody Directory.

Description

TCRβ antibody, clone H57-597, recognizes the beta chain of the T cell receptor (TCRβ), expressed on αβ thymocytes and T lymphocytes, as well as natural killer T (NKT) cells1. TCRβ is a transmembrane protein that consists of an amino-terminal variable region, a constant region, and a stalk segment covalently linked to the TCR alpha chain (TCRα) via a disulfide bond2. TCRα/β does not contain signaling domains and is instead noncovalently associated with the CD3 complex (TCR-CD3), essential for TCR signaling3,4. TCRα/β recognizes antigens bound to major histocompatibility complex (MHC) molecules, resulting in phosphorylation of CD3 ITAMs and subsequent T cell activation, proliferation, and survival5,6.

Biological Information

  • Clonality: Monoclonal
  • Reactivity: Mouse
  • Antigen: TCRβ is expressed on αβ thymocytes, peripheral T cells, and NKT cells.
  • Clone: H57-597
  • Conjugate: DyLight® 550
  • Isotype: IgG
  • Gene: 21577

Handling

  • Quantity: 50 µg
  • Storage: This DyLight® 550 conjugate is stable when stored at 2-8°C. Do not freeze.

Applications

  • In Situ Hybridization (ISH)
Specificity rating
Sensitivity rating
Quality rating
Write your own review

Product Overview

Links