Anti-Mouse Vγ2 TCR - Purified <i>In vivo </i>PLATINUM™ Functional Grade
Product Details
- Cat. No.
- T704- 5.0 mg
- Clonality
- Monoclonal
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Description
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules. Clone UC3-10A6 antibody has been shown to deplete γδ T cells when administered in vivo.
Biological Information
- Clonality: Monoclonal
- Reactivity: Mouse
- Antigen: Vγ 2 T-Cell Receptor (TCR)-bearing T lymphocytes make up a significant proportion of γδ TCR-bearing cells in the late fetal and adult thymus and adult peripheral lymphoid tissues and lung.
- Clone: UC3-10A6
- Conjugate: Low Endotoxin Functional Formulation, PLATINUM
- Isotype: IgG
- Gene: 110067
Handling
- Quantity: 5.0 mg
- Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Applications
- In Situ Hybridization (ISH)