Product & ReviewsAntibodies

anti-MRP14/S100A9/calgranulin B mouse monoclonal, 47-8D3, purified

Product Details

Cat. No.
691519
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
PROGEN

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Description

47-8D3 reacts with macrophages and detects the well-known leukocyte L1, cystic fibrosis antigen. Detecting a single protein band of 14 kDa in Western blots of lysates of human monocytes and granulocytes, the antigen was identified as the calcium-binding protein MRP14, which is a member of the S100 family involved a.o. in regulating the cell cycle. MRP14 is also implicated in the abnormal differentiation of myeloid cells in the stroma of cancer. It is further found on squamous mucosal epithelia

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Cat (Feline), Dog (Canine), Goat, Guinea Pig, Horse (Equine), Human, Monkey, Pig (Swine), Rabbit (Lapine), Rat
  • Antigen: human peripheral blood monocyte components derived by affinity chromatography with Sepharose 4B coupled to rabbit monocyte antibodies
  • Clone: 47-8D3
  • Conjugate: unconjugated
  • Isotype: IgG1 kappa

Handling

  • Quantity: 1 mL (100 µg/ml)
  • Storage: store at 2-8°C

Applications

  • Flow Cytometry (FC)
  • Immunocytochemistry (ICC)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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