Myogenin belongs to a family of myogenic transcription factors, including MyoD, Myf5, and MRF4, which arecritical in muscle development. Myogenin is found strictly in cells of skeletal muscle origin, and is thereforeused as a biomarker for tumours of the muscle lineage, including alveolar rhabdomyosarcomas. Anti-Myogenin staining may occur in Wilms’ tumour, and it labels the nuclei of myoblasts in developing muscletissue. It is also expressed in some leiomyosarcomas
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Recombinant Human Myogenin
- Clone: IHC631
- Conjugate: unconjugated
- Isotype: IgG1 kappa
- Quantity: 1 mL
- Storage: store at 2-8°C
- Immunohistochemistry (IHC)
