Product & ReviewsAntibodies

Anti-NCAM1 monoclonal antibody, clone 123C3 [FITC]

Product Details

Cat. No.
CABT-48169MH
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Creative Diagnostics

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Description

Mouse Anti-Human NCAM1 monoclonal antibody for FC. Mouse anti Human CD56 antibody, clone 123C3 recognizes human neural cell adhesion molecule (NCAM), otherwise known as CD56. The CD56 molecule is a cell surface glycoprotein which is expressed on neuroendocrine cells, natural killer cells and a subset of T cells in the peripheral blood. Three main isoforms of CD56 exist. Neurons express the largest 180kD form, while haemopoietic cells express the 140kD isoform. Mouse anti Human CD56 antibody, clone 123C3 recognizes the 140 and 180kD isoforms of the CD56 protein. In neuronal tissues, CD56 mediates homophilic and heterophilic adhesion and is implicated in neural development. Studies suggest that CD56 is also expressed on thyroid follicular epithelium and may play a role in autoimmune disease of the thyroid. CD56 is expressed in a range of tumours including tumours of the lung, neural derived malignancies and natural killer cell lymphomas. Flow Cytometry Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Applications:FC

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Conjugate: FITC
  • Isotype: IgG1
  • Gene: 4684

Handling

  • Quantity: 100 μg
  • Storage: in frost-free freezers is not recommended. This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • Flow Cytometry (FC)
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