Product & ReviewsAntibodies

Anti-NR3C1 monoclonal antibody, clone 5E4 [FITC]

Product Details

Cat. No.
CABT-49244MH
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Creative Diagnostics

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Description

Mouse Anti-Human NR3C1 monoclonal antibody for FC. Mouse anti Human Glucocorticoid Receptor antibody, clone 5E4 recognizes the human glucocorticoid receptor, also known as Nuclear receptor subfamily 3 group C member 1 (NR3C1), a 777 amino acid receptor bearing 3 distinct functional domains, an N-terminal modulating domain, a DNA binding domain and a C-terminal steroid binding domain. The human glucocorticoid receptor is located either in the cytoplasm of cells, prior to ligand binding associated with certain heat shock proteins, or the nucleus following binding to ligand. Mutations in the glucocorticoid receptor gene can lead to familial glucocorticoid resistance, characterized by elevated plasma cortisol levels. Mouse anti human glucocorticoid receptor antibody, clone 5E4 has been demonstrated to cross-react with the murine glucocorticoid receptor. Flow Cytometry Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Applications:FC

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human, Mouse
  • Conjugate: FITC
  • Isotype: IgG1
  • Gene: 2908

Handling

  • Quantity: 100 μg
  • Storage: in frost-free freezers is not recommended. This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • Flow Cytometry (FC)
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