Anti-OSM polyclonal antibody
Product Details
- Cat. No.
- CPBT-65241RH
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Rabbit anti-Human OSM polyclonal antibody for ELISA, WB. Rabbit anti Human Oncostatin M antibody recognizes human Oncostatin M (OSM), a 209 amino acid pleiotropic cytokine, originally isolated from PMA (phorbol 12-myristate 13-acetate) treated U937 leukaemia cells and mitogen-activated T lymphocytes. OSM was identified by the ability to inhibit the replication of various human tumour cell lines, but has also been shown to exert a stimulatory effect on fibroblasts, smooth muscle cells and Kaposis sarcoma cells, and to induce the release of certain cytokines by endothelial cells. OSM signals through binding with low affinity to the gp130 protein present in two cell surface receptors: type I consisting of gp130 and LIFR (leucocyte inhibitory factor receptor) which also acts as a receptor for LIF, and type II consisting of gp130 and OSMR, which mediates OSM specific activities. Applications：ELISA; WB
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Conjugate: Biotin
- Isotype: Polyclonal IgG
- Gene: 5008
Handling
- Quantity: 50 μg
- Storage: Prior to reconstitution store at +4°C. After reconstitution store at -20°C. This product should be stored undiluted. in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)