Product & ReviewsAntibodies
anti-p53 mouse monoclonal, BP53.12, ascites
Product Details
- Cat. No.
- 18314
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The gene coding for p53 oncoprotein is located on chromosome 17p. Allele loss at this hromosome site has frequently been seen in many tumours including lung, colon, breast and brain. Expression of p53 oncoprotein was not detected in normal mucosa, whereas mutation results in a detectable expression of the p53 protein. It is therefore suggested that immunocytochemical detection of p53 protein is an indication for malignancy.Positive control: Breast carcinoma
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: human recombinant p53 protein
- Clone: BP53.12
- Conjugate: unconjugated
- Isotype: IgG2a
Handling
- Quantity: 1 mL
- Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Applications
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)