anti-p62 / SQSTM1 (C-terminus) guinea pig polyclonal + anti-guinea pig IgG HRP set
Product Details
- Cat. No.
- 71001
- Type
- Primary Antibody
- Clonality
- Polyclonal
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Description
anti-p62 antibody:The anti-p62 antibody is useful for research in ubiquitin-associated degradation and autophagy and for detection of neurofibrillary tangles in the brain of Alzheimer disease patients, in Parkinson diseases and various chronic liver diseases.Human 62 kD (p62) protein, is present in intracytoplasmic inclusions (e.g. hyaline bodies) of hepatocellular carcinoma. p62 protein (also described as ubiqutin-binding protein; sequestosome 1; SQSTM1) has been found in many tissues and cells, including lymphoid cells, serving probably a common cellular signal transduction mechanism (e.g. ubiquitin-associated degradation and autophagy). The antiserum stains also neurofibrillary tangles in the brain of patients suffering from Alzheimer’s disease.anti-guinea pig IgG goat polyclonal, HRP conjugate:Whole Guinea Pig IgG secondary antibodies are isolated from antisera by immunoaffinity chromatography. The antibody is conjugated to Horseradish peroxidase (HRP) and is commonly used for WB, IHC and ELISA. Based on immunoelectrophoresis and/or ELISA, the antibody reacts with whole molecule guinea pig IgG. It also reacts with the light chains of other guinea pig immunoglobulins. No antibody was detected against non-immunoglobulin serum proteins. The antibody may cross-react with immunoglobulins from other species.Set content: Cat. No. GP62-C, anti-p62 / SQSTM1 (C-terminus) guinea pig polyclonal, serumCat. No. 90001, anti-guinea pig IgG goat polyclonal, HRP conjugate
Biological Information
- Clonality: Polyclonal
- Antigen: see individual antibody datasheet for information about specific immunogens
Handling
- Quantity: 100 µl anti-p62 + 100 µg anti-guinea pig IgG HRP
- Storage: lyophilized at 2-8°C, reconstituted at -20°C (avoid freeze and thaw cycles)