Human 62 kD (p62) protein, is present in intracytoplasmic inclusions (e.g. hyaline bodies) of hepatocellular carcinoma. p62 protein (also described as ubiqutin-binding protein; sequestosome 1; SQSTM1) has been found in many tissues and cells, including lymphoid cells, serving probably a common cellular signal transduction mechanism (e.g. ubiquitin-associated degradation and autophagy)
- Clonality: Polyclonal
- Host: Guinea Pig
- Reactivity: Human, Mouse, Pig (Swine), Rat
- Antigen: C-terminal domain (20 amino acids: C-NYD IGA ALD TIQ YSK HPP PL) of human p62 protein, coupled to KLH. This peptide sequence is identical in human, monkey, bovine, mouse, and rat.
- Conjugate: unconjugated
- Quantity: 100 µL
- Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blotting (WB)