p97 ATPase / VCP (also described as valosin-containing protein) is implicated in homotypic membrane fusion events and is related to the N-ethyl maleimide-sensitive fusion protein NSF/Sec18p. The antibody reacts with the p97 subunit of 15S Mg2+-ATPase. p97/VCP is involved in ubiquitin-proteasome dependent protein degradation processes and involvement was also found e.g. in the formation of neuronal inclusion bodies in neuro-degenerative diseseases (e.g. Parkinson’s disease)
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Rabbit (Lapine), Rat, Xenopus
- Antigen: 15S Mg2+ ATPase complex purified from Xenopus laevis ovary
- Clone: 58.13.3
- Conjugate: unconjugated
- Isotype: IgG1
- Quantity: 50 µg
- Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
