Product & ReviewsAntibodies
anti-PD-L1 rabbit monoclonal, IHC411, purified
Product Details
- Cat. No.
- 691736
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rabbit
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Description
Programmed Death-Ligand 1 (PD-L1), CD274, or B7 Homolog 1 (B7-H1), is a transmembrane protein involvedin suppressing the immune system and rendering tumour cells resistant to lysis through binding of theProgrammed Death-1 (PD-1) receptor. Overexpression of PD-L1 may allow cancer cells to evade the actions ofthe host immune system. In renal cell carcinoma, upregulation of PD-L1 has been linked to increased tumouraggressiveness and risk of death
Biological Information
- Clonality: Monoclonal
- Host: Rabbit
- Reactivity: Human
- Antigen: Recombinant Human PD-L1
- Clone: IHC411
- Conjugate: unconjugated
- Isotype: IgG
Handling
- Quantity: 1 mL
- Storage: store at 2-8°C
Applications
- Immunohistochemistry (IHC)