The mabs react with plakophilin 2, a member of the arm-repeat family of proteins which can occur in at least 2 splice forms (2a and 2b). Plakophilin 2 assembles with other proteins to form the desmosomal plaque in simple and glandular epithelia, the basal layer of certain stratified epithelia, all layers of some stratified epithelia, and in nonepithelial desmosome-possessing tissues such as myocardium, Purkinje fibers, and dendritic reticulum of lymph node follicles
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Bovine, Human, Rat
- Antigen: synthetic carboxyterminal peptide (24 aa) of human plakophilin 2
- Clone: PP2/62 + PP2/86 + PP2/150
- Conjugate: unconjugated
- Isotype: IgG1
- Quantity: 5 mL
- Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blotting (WB)