Product & ReviewsAntibodies
Anti-Rat ALK-7 (Clone 118310)
Product Details
- Cat. No.
- A379
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Activin receptor-like kinase (ALK) 7 is a type I serine/threonine kinase receptor of the transforming growth factor (TGF)-beta family of proteins.1 ALK7 is most abundantly expressed in human brain, pancreas and colon.2 It negatively regulates glucose-stimulated insulin release in β-cells3 and plays an important role in regulating the functional plasticity of pancreatic islets.3 ALK7 also has an important role in the regulation of body fat deposition. These has implications for the development of treatments against diabetes and obesity.3
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Rat
- Clone: 118310
- Conjugate: Purified No Carrier Protein
- Isotype: IgG2a
- Gene: 245921
Handling
- Quantity: 25 µg, 500 µg
- Storage: The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Applications
- Western Blotting (WB)