Product & ReviewsAntibodies

Anti-Rat IL-1 Rrp2

Product Details

Cat. No.
I-680-25 µg
Clonality
Monoclonal
Host
Mouse
Leinco Technologies

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Description

Interleukin-1 receptor related protein 2 (IL-1 Rrp2) is a receptor for IL-1F6 which is a proinflammatory member of IL-1 family. IL-1F8, and IL-1F9 also signal through IL-1Rrp2 and IL-1RAcP.1 IL-1F6, IL-1F8 and Il-1F9 are agonists and, along with their receptor IL-1Rrp2, are highly expressed in epithelial cells suggesting a role in immune defense in the skin and the gastrointestinal (GI) tract including the mouth. Synovial fibroblasts and articular chondrocytes also express IL-1Rrp2 and respond to IL-1F8, indicating a possible role in rheumatoid arthritis (RA).2

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Rat
  • Clone: 131011
  • Conjugate: Purified No Carrier Protein
  • Isotype: IgG1
  • Gene: 171106

Handling

  • Quantity: 25 µg
  • Storage: The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.

Applications

  • Neutralization (Neut)
  • Western Blotting (WB)
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