Product & ReviewsAntibodies

Anti-Rat Jagged-1 (Clone 72017)

Product Details

Cat. No.
J108-25 µg
Clonality
Monoclonal
Host
Mouse
Leinco Technologies

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Description

Jagged 1 (JAG1) is a cell surface protein that functions in an embryologically important signaling pathway, known as the Notch signaling pathway, which is a highly conserved cell signaling system.1 JAG1 plays an essential role in tissue formation during embryonic development of primitive organisms.2 JAG1 is a strong candidate gene for Alagille syndrome (AGS)3 which is an autosomal dominant disorder with developmental abnormalities affecting the liver, heart, eyes, vertebrae, and craniofacial region.4

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Rat
  • Clone: 72017
  • Conjugate: Purified No Carrier Protein
  • Isotype: IgG1
  • Gene: 29146

Handling

  • Quantity: 25 µg
  • Storage: The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.

Applications

  • In Situ Hybridization (ISH)
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