Product & ReviewsAntibodies
Anti-Rat Jagged-1 (Clone 72017)
Product Details
- Cat. No.
- J108- 500 µg
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Jagged 1 (JAG1) is a cell surface protein that functions in an embryologically important signaling pathway, known as the Notch signaling pathway, which is a highly conserved cell signaling system.1 JAG1 plays an essential role in tissue formation during embryonic development of primitive organisms.2 JAG1 is a strong candidate gene for Alagille syndrome (AGS)3 which is an autosomal dominant disorder with developmental abnormalities affecting the liver, heart, eyes, vertebrae, and craniofacial region.4
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Rat
- Clone: 72017
- Conjugate: Purified No Carrier Protein
- Isotype: IgG1
- Gene: 29146
Handling
- Quantity: 500 µg
- Storage: The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Applications
- In Situ Hybridization (ISH)