Anti-SPN monoclonal antibody, clone DFT-1 [R-PE]
Product Details
- Cat. No.
- CABT-46071MH
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Mouse Anti-Human SPN monoclonal antibody for FC. Mouse anti Human CD43 antibody, clone DFT-1 recognizes human CD43 also known as leukosialin or sialophorin. CD43 is a 381 amino acid single pass type I transmembrane glycoprotein present on the cell surface of multiple cell types including thymocytes, T-lymphocytes, neutrophils, plasma cells and platelets. It is lacking on the surface of most lymphocytes. CD34 is a major membrane sialoglycoprotein expressed on T lymphocytes as two predominant glycoforms, a 115kDa form present on all T-cells and a 130kDa form indicitive of T-cell activation and acts as a T-cell counter-receptor for CD169/Siglec-1. Clone DFT-1 binds to both glycoforms of human CD43. CD34 expression is deficient and/or defective in patients suffering from the X-linked chromocomal immunodeficiency condition Wiskott-Aldrich syndrome and acts as a ligand for CD54.Mouse anti human CD43, clone DFT-1 has been used successfully for the evaluation of CD43 expression in patients with Myelodysplastic syndromes. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood Applications：FC
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Conjugate: R-PE
- Isotype: IgG1
- Gene: 6693
Handling
- Quantity: 100 Tests
- Storage: Prior to reconstitution store at +4°C. Following reconstitution store at +4°C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)