Substance P occurs in nerve fibers of the central and peripheral nervous system and in endocrine cells of the gut. It stimulates smooth muscle contraction, gives rise to vasodilation and is involved in sensory functions. Substance P-containing tumors arising in the ileum are often associated with the carcinoid syndrome, characterized by flushing of the skin, diarrhea, broncho-constriction and sudden drops in blood pressure
- Clonality: Polyclonal
- Host: Guinea Pig
- Reactivity: Rat
- Antigen: substance P (code 7451, Peninsula, USA), conjugated to BSA
- Conjugate: unconjugated
- Quantity: 50 µL
- Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
- Immunohistochemistry (IHC)
