Product & ReviewsAntibodies
anti-TFE3 mouse monoclonal, IHC672, purified
Product Details
- Cat. No.
- 691750
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Transcription Factor E3 (TFE3) is a transcription factor that binds to the MUE3-type E-box sequences involvedin TGF-ß signaling. Anti-TFE3 staining is the most sensitive and specific indicator of Xp11 translocationrenal cell carcinomas. Since alveolar soft part sarcoma (ASPS) is characterized by a specific chromosomalrearrangement resulting in a chimeric transcription factor (ASPSCR1-TFE3), this TFE3 IVD antibody is also auseful diagnostic tool for recognizing ASPS
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Recombinant Human TFE3
- Clone: IHC672
- Conjugate: unconjugated
- Isotype: IgG1
Handling
- Quantity: 1 mL
- Storage: store at 2-8°C
Applications
- Immunohistochemistry (IHC)