Product & ReviewsAntibodies
anti-TGF-alpha mouse monoclonal, 1E8-G6, purified
Product Details
- Cat. No.
- 691508
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
1E8-G6 reacts with TGF-alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. 1E8-G6 is completely blocked by the peptide used for immunization. TGF-alpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype. In sections both cytoplasma and cell membranes are stained
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Rabbit (Lapine), Zebrafish
- Antigen: synthetic TGF-alpha 34-43 decapeptide linked carrier
- Clone: 1E8-G6
- Conjugate: unconjugated
- Isotype: IgM kappa
Handling
- Quantity: 1 mL (100 µg/ml)
- Storage: store at 2-8°C
Applications
- ELISA (ELISA)
- Flow Cytometry (FC)
- Immunohistochemistry (IHC)