Product & ReviewsAntibodies

Anti-THY1 monoclonal antibody, clone OX-7 [Biotin]

Product Details

Cat. No.
CABT-49755MR
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Creative Diagnostics

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Description

Mouse Anti-Rat THY1 monoclonal antibody for FC. Mouse anti Rat CD90 antibody, clone OX-7 recognizes rat and CD90, also known as Thy1.1, a GPI-anchored membrane protein containing a single V type Ig-like domain CD90 is expressed on a variety of cell types including thymocytes, neuronal cells, stem cells, immature B cells and connective tissues, CD90 is also expressed in T cells in mice. Since Thy1.1 is a monomorphic determinant in rat but polymorphic in mice, clone MRC OX-7 reacts with Thy1.1 mice e.g. AKR and FVB mice, but not Thy1.2 mice such as CBA and BALB/c. The affinity of the Fab of MRC OX-7 for rat Thy1 is 3 x 109m1 and for mouse Thy1.1 is 3 x 108m-1(1). Mouse anti rat CD90, clone MRC OX-7 has been demonstrated to promote neurite outgrowths on peripherin-stained sympathetic rat neurons, using fluorescence microscopy. Clone OX-7 has also been reported to induce glomerular nephritis in Wistar rats. This product is routinely tested in flow cytometry on rat thymocytes. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul. Applications:FC

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Guinea Pig, Mouse, Rabbit (Lapine), Rat
  • Conjugate: Biotin
  • Isotype: IgG1
  • Gene: 24832

Handling

  • Quantity: 100 μg
  • Storage: in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • Flow Cytometry (FC)
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