Anti-TIMP1 polyclonal antibody [Biotin]
Product Details
- Cat. No.
- CPBT-65287RH
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Rabbit anti-Human TIMP1 polyclonal antibody for ELISA, WB. Rabbit anti Human TIMP-1 antibody specifically recognizes human TIMP-1 (Tissue Inhibitor of Metalloproteinase -1), a secreted glycoprotein and member of the protease inhibitor I35 (TIMP) family, which is expressed by a wide range of cells, including microvascular endothelial cells, smooth muscle cells, mesangial cells, and some fibroblasts. TIMP-1 acts as a natural extracellular inhibitor of MMPs (matrix metalloproteinases), a group of peptidases involved in degradation of the extracellular matrix, and is also involved in erythropoiesis, through the simulation of the proliferation/differentiation of erythroid progenitors. Studies have shown that a correlation between localized concentrations of TIMP-1 and TIMP-3, may determine cell fate, and that increased expression of TIMP-1, may act as an inhibitor/suppressor of invasive cell growth. ELISA This biotinylated human TIMP-1 antibody may be used in a direct ELISA or as the detection reagent in a sandwich ELISA. Applications：ELISA; WB
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Conjugate: Biotin
- Isotype: Polyclonal IgG
- Gene: 7076
Handling
- Quantity: 50 μg
- Storage: in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)
- Immunocytochemistry (ICC)
- Immunofluorescence (IF)