Product & ReviewsAntibodies

Anti-TNFSF4 monoclonal antibody, clone ATM-2 [R-PE]

Product Details

Cat. No.
CABT-47410MR
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Creative Diagnostics

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Description

Mouse Anti-Rat TNFSF4 monoclonal antibody for FC. Mouse anti Rat CD252 antibody, clone ATM-2 specifically recognizes rat CD252, otherwise known as OX40L or CD134L, a 22kDa type II transmembrane glycoprotein and member of the TNF superfamily, expressed by antigen-presenting cells including activated dendritic cells and B cells, and also by vascular endothelium. The interaction of CD252 with its receptor OX40/CD134, acts as a co-stimulator of T cell activation, proliferation and both Th1 and Th2 cytokine production, and is also important in activated B cell proliferation and secretion of immunoglobulins (Igs). CD252/OX40 interaction has been implicated in HTLV-1 associated diseases including myelopathy and adult T cell leukaemia, and also with the autoimmune diseases rheumatoid arthritis and inflammatory bowel disease. Mouse anti Rat CD252 antibody, clone ATM-2 has been shown to block the co-stimulatory activity of CD252 on rat T cell proliferation. Flow Cytometry Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Applications:FC

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Rat
  • Conjugate: R-PE
  • Isotype: IgG1
  • Gene: 89814

Handling

  • Quantity: 100 Tests
  • Storage: Prior to reconstitution store at +4°C. After reconstitution store at +4°C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • ELISA (ELISA)
  • Flow Cytometry (FC)
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