Product & ReviewsAntibodies
anti-Transferrin Receptor mouse monoclonal, PAL-M1, supernatant
Product Details
- Cat. No.
- 10822
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Can be used to discriminate between malignant cutaneous melanoma and nevocellular nevi. PAL-M1 recognizes the transferrin receptor (TFR, CD71), a marker for tumor progression in the melanocytic lineage and stains the majority of primary melanomas and their metastases. Local staining of dysplastic nevocellular nevi may be observed. Common nevocel­lular nevi rarely stain. Excellent marker for neoplastic progression of melanocytic proliferation. Reactivity on cultured cell lines: Melanoma cell lines Mel 57, CM 136, M14, BLM; HepG2, PLC, Daudi, Raji, PBLPositive control: Human Melanoma.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse
- Antigen: isolated from human melanoma cells
- Clone: PAL-M1
- Conjugate: unconjugated
- Isotype: IgG1
Handling
- Quantity: 1 mL
- Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Applications
- Immunohistochemistry (IHC)