Product & ReviewsAntibodies

Anti-WNT3A polyclonal antibody

Product Details

Cat. No.
CPBT-65710RH
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Creative Diagnostics

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Description

Rabbit anti-Human WNT3A polyclonal antibody for ELISA, WB. Rabbit anti Human WNT-3a antibody specifically recognizes human WNT-3a, a secreted protein and member of the Wnt family of signalling proteins, which acts as a ligand for members of the frizzled family of seven transmembrane receptors, and plays key roles in many developmental and cell fate decisions, including embryonic patterning, CNS development, and cytoskeletal formation. Wnt-3a acts as a promoter of the proliferation of ventral midbrain dopaminergic neuron precursor cells, and has been implicated in the progressive differentiation of anterior neural cells, as well as regulating the survival and expansion of neural progenitors derived from human embryonic stem cells. Wnt3a has been shown to act upstream of the Notch signalling pathway, in the regulation of somitogenesis, which is believed to be controlled by a segmentation clock, consisting of molecular oscillators in the Notch, Wnt3a and Fgf8 pathways. ELISA may be used in a direct ELISA or as the detection antibody in a sandwich ELISA. Applications:ELISA; WB

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human
  • Conjugate: Biotin
  • Isotype: Polyclonal IgG
  • Gene: 89780

Handling

  • Quantity: 50 μg
  • Storage: in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • Flow Cytometry (FC)
  • Immunocytochemistry (ICC)
  • Immunofluorescence (IF)
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