Product & ReviewsAntibodies

Apaf-1 (N-term) Antibody

Product Details

Cat. No.
250543
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Abbiotec

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Description

Apoptosis protease activating factor-1 (Apaf-1) mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3) by forming oligomer upon binding with cytochrome c and dATP. Oligomeric Apaf-1 binds to pro-caspase 9 through their N-terminal CARD domains releasing mature caspase-9.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human, Mouse, Rat
  • Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Apaf-1.
  • Isotype: Rabbit Ig
  • Gene: O14727

Handling

  • Quantity: 0.1 mg
  • Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Immunohistochemistry (IHC)
  • Immunoprecipitation (IP)
  • Western Blotting (WB)
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