APBA1 Antibody
Product Details
- Cat. No.
- 252076
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Amyloid beta A4 precursor protein-binding family A member 1 (APBA1) functions in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. APBA1 modulates processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. APBA1 is composed of an N-terminal domain that binds Munc18-1 and LIN-2/CASK, a middle phosphotyrosine-binding domain (PID/PTB) that mediates binding with the cytoplasmic domain of the beta-amyloid precursor protein, and two C-terminal PDZ domains thought to attach proteins to the plasma membrane.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human APBA1.
- Isotype: Rabbit Ig
- Gene: Q02410
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)