Product & ReviewsAntibodies
APC Antibody
Product Details
- Cat. No.
- 200132
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
The adenomatous polyposis coli protein (APC) is a tumor suppressor that promotes rapid degradation of catenin-beta 1 (CTNNB1) and participates in Wnt signaling. The GSK3-beta protein kinase regulates its activity by phosphorylation. APC binds to PDZ domains of DLG1 and 3, to catenins, axin and MAPRE protein family including the EB members.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat, Xenopus
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human APC.
- Clone: ABT-1033
- Isotype: Rabbit Ig
- Gene: P25054, NP_000029
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)