Product & ReviewsAntibodies
APC Antibody
Product Details
- Cat. No.
- 250131
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
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Description
The adenomatous polyposis coli protein (APC) is a tumor suppressor that promotes rapid degradation of catenin-beta 1 (CTNNB1) and participates in Wnt signaling. The GSK3-beta protein kinase regulates its activity by phosphorylation. APC binds to PDZ domains of DLG1 and 3, to catenins, axin and MAPRE protein family including the EB members. This antibody recognizes an epitope in the C-terminal half of the mouse APC in ELISA, Western blot and immunofluorescent staining.
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Mouse
- Antigen: Recombinant mouse APC[2170-2394] protein
- Clone: KT45
- Isotype: rat IgG2a
- Gene: Q61315, NP_031488
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunofluorescence (IF)
- Western Blotting (WB)