Apo-E Antibody
Product Details
- Cat. No.
- 250544
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Apolipoprotein E (Apo-E) is a protein component of plasma lipoprotein that mediates the binding, internalization and catabolism of lipoprotein particles. Apo-E can serve as a ligand for the LDL (Apo-B/E) receptor and for the specific Apo-E receptor (chylomicron remnant) of hepatic tissues. Apo-E is present in all lipoprotein fractions in plasma and constitutes 10-20% of very low density lipoproteins (VLDL) and 1-2% of high density lipoproteins (HDL) . Apo-E is produced in most organs. Defects in Apo-E are a cause of hyperlipoproteinemia type III (lipid deposits in palms, tendons and elbows), sea-blue histiocyte disease (splenomegaly, thrombocytopenia), and lipoprotein glomerulopathy.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of mouse Apo-E.
- Isotype: Rabbit Ig
- Gene: P02649
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)