ApoA5 (4H8H) Antibody
Product Details
- Cat. No.
- 252597
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
ApoA5 (Apolipoprotein A5) is a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50–70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of human APOA5 expressed in E. coli.
- Clone: 4H8H8E2 (c)
- Isotype: Mouse IgG1
- Gene: Q6Q788
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)