Product & ReviewsAntibodies
APOBEC2 rabbit antibody (pAb)
Product Details
- Cat. No.
- 39985
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
APOBEC2 (Apolipoprotein B mRNA-editing enzyme catalytic subunit 2) is part of a family of enzymes that edit nucleic acids, possibly changing cytosine to uracil. APOBEC2 expression is regulated by TNF-a via NFκB activation and suggest a possible role of APOBEC2 in the pathophysiology of hepatic inflammation. APOBEC2 has a low intrinsic cytidine deaminase activity and is also involved in DNA demethylation. APOBEC2 deaminates 5-methylcytosine, followed by base excision repair by Mbd4.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Isotype: IgG
Handling
- Quantity: 100 ul
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Western Blotting (WB)