ARL13B Antibody
Product Details
- Cat. No.
- 17711-1-AP
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Immunofluorescent analysis of ( 4% PFA ) fixed MDCK cells using 17711-1-AP(ARL13B antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Description
ARL13B, also named as ARL2L1, is a small ciliary G protein of the Ras superfamily. Localized in the cilia, it is required for cilium biogenesis and sonic hedgehog signaling. Defects in ARL13B are the cause of Joubert syndrome (JS) which is an autosomal recessive disorder characterized by a distinctive cerebellar malformation (PMID: 19906870).This antibody detects two specific bands at 60 kDa and 48 kDa. Arl13b is predicted to be a 48 kDa protein, and the 60 kDa band is likely to represent a modified form of Arl13b. ARL13B can be used to mark the cilia (PMID:22072986).
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Chicken, Dog (Canine), Human, Mouse, Pig (Swine), Rat, Sheep (Ovine), Xenopus, Zebrafish
- Isotype: IgG
- Gene: 200894
Handling
- Storage: Store at -20°C. Aliquoting is unnecessary for -20°C storage.
- Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
- Specificity: 5
Applications
- ELISA (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blotting (WB)
This antibody reliably works great!
Immunofluorescence and WB
This antibody works great with little background. IF 1:100 WB 1:1000
Review Date: 30 Aug 2018 | Proteintech Group
